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Various factors, including hyperglycemia, lipid accumulation, oxidative stress, hypoxia, RAAS, ER stress, inflammation, EMT and programmed cell death, have been shown to induce renal tubular injury and contribute to the progression of DKD

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Retatrutide is an investigational drug currently in Phase 3 clinical trials and has not been FDA-approved

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Lack of Sleep and Energy Getting enough sleep every night, approximately 8 hours, is just as important as making diet and exercise changes